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Scurvy in the US

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SUMMARY

The incidence of scurvy in the United States has significantly increased, rising from 8.2 per 100,000 in 2016 to 26.7 per 100,000 in 2020, particularly affecting children under 18 years old. A study analyzing data from 19,413,465 patients revealed that 265 were diagnosed with scurvy, with a majority being male (69.8%) and belonging to the lowest income quartile (36.5%). Notably, 64.2% of affected individuals also had a diagnosis of autism spectrum disorder. The findings highlight a concerning trend in nutritional deficiencies among vulnerable populations.

PREREQUISITES
  • Understanding of scurvy and its clinical manifestations
  • Familiarity with demographic analysis in public health studies
  • Knowledge of nutritional epidemiology
  • Awareness of socioeconomic factors affecting health outcomes
NEXT STEPS
  • Research the nutritional requirements to prevent scurvy, focusing on vitamin C intake
  • Investigate the correlation between socioeconomic status and health outcomes in pediatric populations
  • Examine the impact of urban versus rural living conditions on dietary access and health
  • Explore the relationship between autism spectrum disorder and nutritional deficiencies
USEFUL FOR

Public health professionals, pediatricians, nutritionists, and researchers focusing on childhood health and nutritional epidemiology will benefit from this discussion.

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The Troubling Rise of Scurvy: A Review and National Analysis of Incidence, Associated Risk Factors, and Clinical Manifestations​


Results:​

The incidence of scurvy increased over the study period, from 8.2 per 100,000 in 2016 to 26.7 per 100,000 in 2020. Patients with scurvy were more likely to be younger (P < 0.001), male (P = 0.010), in the lowest income quartile (P = 0.013), and obese (P < 0.001). A majority (64.2%) had a concomitant diagnosis of autism spectrum disorder.

Verdreifachung in fünf Jahren - Wiederaufleben von Skorbut auch bei Kindern in den USA​

Einen Monat nach unserem Bericht über einen ungewöhnlichen Fall, bei dem sich Skorbut als Ursache für Gangstörungen bei einem Kleinkind entpuppte [Mutschler U. Pädiatrie. 2024;36(3):17] haben Forschende des Boston Children's Hospital eine umfassende Übersichtsarbeit zu Skorbut bei Kindern in den USA veröffentlicht.
...
In die Studie eingeschlossen werden konnten alle Patientinnen und Patienten unter 18 Jahren im Zeitraum von 2016 bis 2020. Insgesamt wurden Daten von 19.413.465 Patientinnen und Patienten analysiert, wobei 265 die Diagnose Skorbut erhielten. Die Inzidenz von Skorbut stieg im Laufe der fünf untersuchten Jahre von 8,2 pro 100.000 (2016) auf 26,7 pro 100.000 Kinder (2020). Das Durchschnittsalter der an Skorbut Erkrankten betrug 2,15 Jahre. Die Mehrzahl war männlich (69,8 %) und gehörte dem untersten Einkommensquartil (36,5 %) an.

Translation:

Tripled in Five Years - Resurgence of Scurvy in Children in the USA​


One month after our report of an unusual case in which scurvy was found to be the cause of gait disturbances in a toddler [Mutschler U. Pediatrics. 2024;36(3):17], researchers at Boston Children's Hospital have published a comprehensive review of scurvy in children in the USA.

...

All patients under the age of 18 between 2016 and 2020 were eligible for inclusion in the study. A total of 19,413,465 patients were analyzed, of which 265 were diagnosed with scurvy. The incidence of scurvy increased over the five years studied from 8.2 per 100,000 (2016) to 26.7 per 100,000 children (2020). The average age of those affected by scurvy was 2.15 years. The majority were male (69.8%) and belonged to the lowest income quartile (36.5%).

Comment: What?
 
In the Conclusion
"Relevant demographic factors associated with scurvy identified in this study include male sex and family income in the bottom quartile."
But family income table states that the lowest quartile incidents of scurvy was 36,5%, while the highest was 28,8%, with the intermediate had incident values of 13.5% and 21.2 %. Should the association with income in the lowest quartile and scurvy have been emphasized, as it seems to indicate that nutritional substitution is occurring with only the 'poor'.

Also,

Incidence and Demographics​

No notable associations were observed between scurvy diagnosis and race, residential setting (urban/rural), or payer.
Yet in the supplied table:
Rural 7.7%
Urban 92.3%
Does that not indicate that an association is evident, which the study failed to investigate, perhaps the reason being of not having the data to explain the residential setting percentages.
 

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